Why the study?
Do anti-anginal agents reduce adverse outcomes in patients with silent myocardial ischaemia?
Population
Patients with coronary artery disease and unrecognized or silent myocardial ischaemia
Design
Review
Authors
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Should not yet change management of silent ischaemia; supports randomized trials of suppression.
Do anti-anginal agents reduce adverse outcomes in patients with silent myocardial ischaemia?
Silent myocardial ischaemia is a strong independent predictor of adverse outcomes in coronary artery disease, and its suppression with anti-anginal therapy may improve prognosis.
Carl J. Pepine (1993) studied this question.
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