What does this research mean for the field?

Patients with apparently idiopathic ventricular tachycardia frequently possess underlying macroscopic or microscopic ventricular abnormalities, and this underlying myocardial disease is often progressive despite optimal control of the arrhythmia. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To examine the anatomical substrate of idiopathic ventricular tachycardia in patients without apparent heart disease.

April 1, 1985European Heart Journal

Morphological findings in apparently idiopathic ventricular tachycardia. An echocardiographic haemodynamic and histologic study

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Why the study?

What are the underlying morphological and histological findings in patients with apparently idiopathic ventricular tachycardia?

Key Points

To examine the anatomical substrate of idiopathic ventricular tachycardia in patients without apparent heart disease.
Ten patients with chronic recurrent ventricular tachycardia were evaluated.
Echocardiographic, haemodynamic, and histologic studies were performed on all patients.
Endomyocardial biopsies were conducted to assess myocardial changes.
In seven patients with left bundle branch block morphology, four exhibited signs of arrhythmogenic right ventricular dysplasia or right ventricular cardiomyopathy.
Out of the remaining three cases, one had histologic evidence of myocarditis and another developed dilated cardiomyopathy.
Some patients demonstrated macroscopic or microscopic ventricular abnormalities, indicating that myocardial disease may be progressive despite effective VT control.

Structured PICO

What are the underlying morphological and histological findings in patients with apparently idiopathic ventricular tachycardia?

Population

10 patients with chronic recurrent ventricular tachycardia (VT) and no apparent sign of heart disease (5 males, 5 females: mean age = 40 +/- 11 years).

Intervention

Echocardiographic, haemodynamic and histologic study (including endomyocardial biopsy)

Outcome

Anatomic substrate and morphological findingssurrogate

Patients with apparently idiopathic ventricular tachycardia frequently have underlying structural or histological myocardial disease that may be progressive.

Discussion

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Implication

May indicate occult myocardial disease in apparently idiopathic VT; hypothesis-generating pending larger prospective studies.

Cite This Study

Morgera et al. (1985) studied this question.

synapsesocial.com/papers/6a163f0cf508cb2fcbc1f02d https://doi.org/10.1093/oxfordjournals.eurheartj.a061859

Topics

Myocarditis Echocardiography Cardiomyopathy

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Morphological findings in apparently idiopathic ventricular tachycardia. An echocardiographic haemodynamic and histologic study

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Topics

Morphological findings in apparently idiopathic ventricular tachycardia. An echocardiographic haemodynamic and histologic study

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider