What is the clinical evidence from this study?

Study design: Case Report. Population: Arrhythmogenic right ventricular cardiomyopathy (n=1). Intervention: Targeted radiofrequency ablation and electroanatomic mapping.

What does this research mean for the field?

Dual ventricular tachycardia morphologies and advanced electroanatomic mapping can reveal concealed arrhythmogenic cardiomyopathy masquerading as idiopathic RVOT-VT, which can be successfully treated with targeted radiofrequency ablation. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To report a case of arrhythmogenic right ventricular cardiomyopathy masquerading as benign idiopathic right ventricular outflow tract ventricular tachycardia.

September 15, 2026European Heart Journal Supplements

Not So Idiopathic: Rvot Tachycardia as a Herald of Arrhythmogenic Cardiomyopathy Not So Idiopathic: Rvot Tachycardia as a Herald of Arrhythmogenic Cardiomyopathy

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Key result

Targeted RF ablation renders dual VT non-inducible in concealed ACM masquerading as idiopathic RVOT-VT.

Why the study?

Overlapping electrocardiographic patterns may conceal underlying arrhythmogenic cardiomyopathy in patients with apparent idiopathic RVOT arrhythmias, especially when multiple VT morphologies coexist.

Key Points

To report a case of arrhythmogenic right ventricular cardiomyopathy masquerading as benign idiopathic right ventricular outflow tract ventricular tachycardia.
Evaluated a 61-year-old man presenting with hemodynamically unstable wide-complex tachycardia at 250 beats per minute via coronary angiography and 12-lead electrocardiography.
Performed high-density electroanatomic mapping, programmed ventricular stimulation, targeted radiofrequency ablation, and cardiac magnetic resonance imaging.
Electroanatomic mapping revealed low-voltage meso-epicardial areas and two distinct inducible ventricular tachycardia morphologies with >92% pace-mapping concordance successfully rendered non-inducible by ablation.
Cardiac magnetic resonance demonstrated right ventricular fibrofatty replacement, regional dyskinesia, free-wall aneurysms, and a reduced ejection fraction of 41%, fulfilling two major Padua criteria.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

A 61-year-old man presenting with hemodynamically unstable wide-complex tachycardia who was diagnosed with arrhythmogenic right ventricular cardiomyopathy.

Intervention

High-density electroanatomic mapping, targeted radiofrequency ablation, cardiac magnetic resonance imaging, and dual-chamber ICD implantation

Outcome

Diagnosis of arrhythmogenic right ventricular cardiomyopathy and non-inducibility of arrhythmias post-ablation

Dual VT morphologies and advanced electroanatomic mapping can reveal concealed arrhythmogenic cardiomyopathy masquerading as idiopathic RVOT-VT.

Discussion

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Implication

May prompt mapping in atypical RVOT-VT; leaves open prospective validation for concealed ARVC detection.

Cite This Study

Calvanese et al. (2026) conducted a case report in Arrhythmogenic right ventricular cardiomyopathy (n=1). Targeted radiofrequency ablation and electroanatomic mapping was evaluated. Targeted radiofrequency ablation rendered dual VT morphologies non-inducible in a 61-year-old man with concealed arrhythmogenic cardiomyopathy masquerading as idiopathic RVOT-VT.

synapsesocial.com/papers/6aa90187eed42882c1fc1985 https://doi.org/10.1093/eurheartjsupp/suag058.117

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Not So Idiopathic: Rvot Tachycardia as a Herald of Arrhythmogenic Cardiomyopathy Not So Idiopathic: Rvot Tachycardia as a Herald of Arrhythmogenic Cardiomyopathy

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Not So Idiopathic: Rvot Tachycardia as a Herald of Arrhythmogenic Cardiomyopathy Not So Idiopathic: Rvot Tachycardia as a Herald of Arrhythmogenic Cardiomyopathy

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

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