Key result
Uncontrolled blood pressure in male hypertensives was associated with a significantly higher rate of exaggerated blood pressure response during exercise compared to controlled BP (44% vs 0.1%, P=0.003).
Why the study?
Is uncontrolled resting blood pressure associated with an exaggerated blood pressure response during exercise in male hypertensives?
Cross-Sectional (n=85)
Is uncontrolled resting blood pressure associated with an exaggerated blood pressure response during exercise in male hypertensives?
Uncontrolled resting blood pressure is significantly associated with an exaggerated blood pressure response during exercise in hypertensive men.
Answers are grounded in this paper and cite their sources.
Uncontrolled BP associated with exaggerated exercise responses in hypertensive men; hypothesis-generating and requires prospective confirmation before clinical adoption.
BACKGROUND: Blood pressure (BP) control in hypertensives is important in preventing cardiovascular (CV) morbidity and mortality. This work was done to assess control of BP among Nigerian hypertensives at rest and during exercise. MATERIALS AND METHODS: A total of 85 male hypertensives were recruited consecutively and had clinical evaluation and treadmill (TM) exercise testing using the Bruce protocol. Independent t-test, chi-square, and Fisher's exact tests were used to compare patients with controlled and uncontrolled BP using SPSS version 16 software. Adjustment for confounders was by logistic regression and general linear model. RESULTS: Resting systolic BP (rSBP) (mmHg) and resting diastolic BP (rDBP) (mmHg) were significantly lower in the controlled group (115.0 ± 12.29, 133.1 ± 12.27, P = <0.001 and 76.00 ± 6.55, 91.4 ± 8.00, P = <0.001). The proportion of subjects with controlled BP was 37.7%. Adjusted peak SBP (PSBP) during exercise (mmHg) was significantly higher in the uncontrolled than in the controlled group (210.5 ± 27.31, 191.8 ± 20.77, P = 0.001). Adjusted exaggerated blood pressure response (EBPR) was found in 37 subjects (44%) in the uncontrolled group while seven subjects (0.1%) had EBPR in the controlled group (P = 0.003). CONCLUSION: This study shows that EBPR is significantly higher in subjects with uncontrolled BP compared with those with controlled BP. Therefore, good BP control may be the key factor in preventing EBPR in hypertensives.
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Abiodun et al. (2014) conducted a cross-sectional in Essential Hypertension (n=85). Uncontrolled blood pressure vs. Controlled blood pressure was evaluated on Exaggerated blood pressure response (EBPR) during exercise (p=0.003). Uncontrolled blood pressure in male hypertensives was associated with a significantly higher rate of exaggerated blood pressure response during exercise compared to controlled BP (44% vs 0.1%, P=0.003).
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