Aerobic endurance training was associated with approximately 31% higher bilateral internal carotid artery blood flow compared to untrained status in both young and older men (P<0.05).
Cross-Sectional (n=38)
Does aerobic endurance training improve cerebral blood flow and cerebral vascular responsiveness to CO2 in young and older men compared to untrained individuals?
Endurance training is associated with enhanced bilateral internal carotid artery blood flow in both young and older healthy men.
Effect estimate: ≈31% higher
p-value: p=<0.05
We sought to test the hypothesis that brain blood flow and cerebral vascular responsiveness to carbon dioxide (CVR CO2) are greater in aerobically trained young and old individuals compared to their untrained counterparts. In 11 young trained 23 (20–26) years mean (95% confidence interval), 10 young untrained 25 (22–28) years, 8 older trained 65 (61–69) years, and 9 older untrained 67 (64–71) years healthy individuals, Doppler ultrasound of the internal carotid (ICA) and vertebral (VA) artery blood flow were determined, along with middle cerebral artery mean flow velocity (MCA V mean). Bilateral ICA blood flow was higher in trained individuals when compared to untrained (≈31%, P < 0. 05), but was not influenced by age. VA blood flow was not affected by age or cardiorespiratory fitness. MCA V mean was reduced with age 59. 5 (55. 0–64. 1) cm/s young vs 43. 6 (38. 4–48. 9) cm/s old, P < 0. 05 with no significant effect of training observed. MCA CVR CO 2 were not significantly affected by either age or training status, while ICA CVR CO 2 tended to be elevated in the old trained group. These findings indicate that endurance training enhances bilateral ICA but not VA blood flow in both young and older individuals.
Bráz et al. (Sat,) conducted a cross-sectional in Healthy individuals (n=38). Aerobic endurance training vs. Untrained status was evaluated on Bilateral internal carotid artery (ICA) blood flow (≈31% higher, p=<0.05). Aerobic endurance training was associated with approximately 31% higher bilateral internal carotid artery blood flow compared to untrained status in both young and older men (P<0.05).