Key result
ECGs exceeding STEMI thresholds in healthy individuals vary strongly by ethnicity, reaching ~28% in Ghanaian males.
Why the study?
International ECG STEMI thresholds are predominantly based on individuals of Western European descent, necessitating reevaluation across different populations due to ethnic electrocardiographic variability.
Does the prevalence of ECGs exceeding STEMI thresholds in apparently healthy individuals vary by ethnicity?
Population
10 783 apparently healthy subjects of 6 different ethnicities
Comparison
STEMI ECG threshold fulfillment across ethnicities, sexes, and age groups
Design
Multiethnic cohort study
Authors
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May warrant ethnicity-specific STEMI thresholds to limit misdiagnosis; leaves open prospective outcome validation across populations.
Cohort (n=10,783)
Does the prevalence of ECGs exceeding STEMI thresholds in apparently healthy individuals vary by ethnicity?
There is a highly variable, ethnicity-dependent prevalence of ECGs exceeding STEMI thresholds in healthy individuals, which may lead to over- or underdiagnosis of STEMI in non-Western European populations.
Haar et al. (2020) conducted a cohort in Apparently healthy individuals (n=10,783). Ethnicity vs. Western European Dutch was evaluated on Prevalence of ECGs exceeding STEMI thresholds (STE-ECGs). The prevalence of ECGs exceeding STEMI thresholds in apparently healthy individuals is highly ethnicity-dependent, ranging from 2.3-3.0% in Dutch subjects to 21.7-27.5% in young Ghanaian males.
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