Key result
Gene therapy emerges as a promising treatment targeting the underlying molecular mechanisms of AF.
Why the study?
Current treatments for AF remain suboptimal because they do not target the underlying molecular mechanisms, making gene therapy an emerging mechanism-based approach.
Gene therapy is emerging as a promising mechanism-based treatment approach for atrial fibrillation.
Gene therapy for AF merits translational research; leaves open randomized trials to assess clinical safety and efficacy.
Atrial fibrillation (AF) is the most common heart rhythm disorder in adults and a major cause of stroke. Unfortunately, current treatments for AF are suboptimal as they are not targeting the molecular mechanisms underlying AF. In this regard, gene therapy is emerging as a promising approach for mechanism-based treatment of AF. In this review, we summarize recent advances and challenges in gene therapy for this important cardiovascular disease.
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Yoo et al. (2021) conducted a review in Atrial fibrillation. Gene therapy was evaluated. Gene therapy is emerging as a promising approach for the mechanism-based treatment of atrial fibrillation, addressing the molecular mechanisms underlying the disease.
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