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We have examined mixed populations and cloned murine CD4+ T cell lines for their sensitivity to anti-CD3-stimulated suicide. The sensitivity of CD4+ clones to anti-CD3-stimulated suicide is independent of their interleukin-2/interleukin-4 or interferon-gamma secretion profile or their lytic efficiency in anti-CD3 redirected lytic assays.
Russell et al. (Mon,) studied this question.