Key result
Carotid duplex ultrasound screening in patients with significant peripheral arterial disease revealed a 14% prevalence of significant carotid artery stenosis.
Cross-Sectional (n=50)
Significant carotid artery stenosis (≥70%) is present in 14% of patients with severe peripheral arterial disease, suggesting a potential role for screening in this high-risk population, particularly those with diabetes and dyslipidemia.
Answers are grounded in this paper and cite their sources.
May support targeted carotid screening in severe PAD; leaves open need for prospective outcome trials before practice change.
Background: Peripheral arterial disease (PAD) and carotid occlusive disease (COD) are both known to be specific manifestations of atherosclerosis so can be correlated to each other. An important area of investigation is to identify those with significant carotid artery stenosis (CAS) to reduce the risk of cerebrovascular events. Duplex ultrasound scanning (DUS) is considered a valuable imaging modality to evaluate carotid arteries with high sensitivity and specificity and virtually non-existent hazards. Objectives: We investigated the prevalence of significant CAS among patients with severe peripheral vascular disease (PVD) using carotid duplex. Methods: A total of 50 patients with PVD diagnosed as having significant PAD by peripheral angiography (PA) underwent carotid duplex scanning. Data were collected concerning known risk factors. Significant CAS was defined as a stenosis of 70% or greater. Results: The mean age was 61.6 ± 8.5 years, male (88%). Out of the 50 patients with significant PAD, 7 patients (14%) had significant Carotid Stenosis of which 6 patients (12%) had severe stenosis and 1 patient (2%) had totally occluded carotid artery. CAS was correlated with diabetes, hypertension, dyslipidemia, smoking, coronary artery disease and severity of symptoms. On multivariate analysis, Diabetes and Dyslipidemia seemed to have independent influence. Conclusion: Significant CAS is prevalent among patients having significant PVD. Patients with PAD may be a suitable subgroup for screening for CAS using Carotid duplex, especially those with diabetes, dyslipidemia and positive CRP.
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TM et al. (2017) conducted a cross-sectional in Significant atherosclerotic peripheral arterial disease (n=50). Carotid duplex scanning was evaluated on Prevalence of significant carotid artery stenosis (≥70% stenosis). Carotid duplex ultrasound screening in patients with significant peripheral arterial disease revealed a 14% prevalence of significant carotid artery stenosis.
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