Key result
Hospital Frailty Risk Score predicts ~2-fold higher odds of prolonged length of stay in adults.
Why the study?
Previous studies evaluating the Hospital Frailty Risk Score to predict length of stay focused on patients over 75 years of age, leaving its relationship across all adult ages unexplored.
Does the Hospital Frailty Risk Score (HFRS) predict prolonged length of stay in adult patients of all ages?
Cohort (n=756,164)
No
Does the Hospital Frailty Risk Score (HFRS) predict prolonged length of stay in adult patients of all ages?
Effect estimate: OR 1.8-2.2
The Hospital Frailty Risk Score is a reliable predictor of prolonged hospital length of stay across all adult age groups, outperforming or complementing the Charlson Comorbidity Index.
Supports HFRS for prolonged LOS risk stratification in adults; extends validation across ages but leaves prospective outcome impact open.
BACKGROUND: Hospital Frailty Risk Score (HFRS) has recently been used to predict adverse health outcomes including length of stay (LOS) in hospital. LOS is an important indicator for patient quality of care, the measurement of hospital performance, efficiency and costs. Tools to predict LOS may enable earlier interventions in those identified at higher risk of a long stay. Previous work focused on patients over 75 years of age, but we explore the relationship between HFRS and LOS for all adults. METHODS: This is a retrospective cohort study using data from a large acute hospital during the period from 01/01/2010 to 30/06/2018. The study included patients aged 16 years and older. We calculated HFRS for patients who had been previously admitted to the hospital within the previous 2 years. The study developed Logistic Regression models (crude and adjusted) for nine prediction periods of LOS to assess association between (LOS and HFRS) and (LOS and Charlson Comorbidity Index-CCI), using odds ratios, and AUROC to assess model performance. RESULTS: An increase in HFRS is associated with prolonged LOS. HFRS alone or combined with CCI were more important predictor of long LOS in most of periods to predict LOS. However, crude HFRS was superior to the models where HFRS was combined with any other variable for LOS in excess of 21 days, which had AUROCs ranging from 0·867 to 0·890. Regarding eight age groups, crude HFRS remained the first or second most effective predictor of long LOS. HFRS alone or combined with CCI was superior to other models for patients older than 44 years for all periods of LOS; whereas for patients younger than 44 years it was superior for all LOS except 45, 60, and 90 days. CONCLUSION: This study has demonstrated the utility of HFRS to predict hospital LOS in patients across all ages.
No takes yet. Share an insight, caveat, or question.
Kutrani et al. (2025) conducted a cohort in Hospitalized patients (n=756,164). Hospital Frailty Risk Score (HFRS) vs. Charlson Comorbidity Index (CCI) was evaluated on Prolonged length of stay (OR 1.8-2.2). The Hospital Frailty Risk Score effectively predicted prolonged hospital length of stay across all adult age groups, with odds ratios between 1.8 and 2.2 and AUROCs ranging from 0.779 to 0.890.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: