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February 1, 1987Proceedings of the National Academy of SciencesOpen Access

Efficient retrovirus-mediated transfer and expression of a human adenosine deaminase gene in diploid skin fibroblasts from an adenosine deaminase-deficient human.

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Authors

TPTheo D. PalmerStanford UniversityRHRandy A. HockUniversity of WürzburgWOWilliam OsborneHeartlands Hospital

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Cite This Study

Palmer et al. (1987) studied this question.

synapsesocial.com/papers/6a16862bfab796c0bebc0bb5https://doi.org/10.1073/pnas.84.4.1055
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A gene on human chromosome 6 functions in assembly of tissue-specific adenosine deaminase isozymes1978 · 13 citations
  2. 2Living Tissue Formed in Vitro and Accepted as Skin-Equivalent Tissue of Full Thickness1981 · 1,055 citations
  3. 3Retrovirus-mediated transfer of human adenosine deaminase gene sequences into cells in culture and into murine hematopoietic cells in vivo.1986 · 190 citations
  4. 4A transmissible retrovirus expressing human hypoxanthine phosphoribosyltransferase (HPRT): gene transfer into cells obtained from humans deficient in HPRT.1983 · 211 citations
  5. 5Redesign of Retrovirus Packaging Cell Lines To Avoid Recombination Leading to Helper Virus Production1986 · 1,251 citations