Efficacy of Dermocosmetic Combinations in the Treatment of Mild to Moderate Acne Vulgaris: An Open‐Label Study

Introduction Acne is a prevalent skin condition that raises appearance‐related concerns and strongly affects self‐esteem and social interactions. Dermocosmetics can help alleviate treatment‐related side effects and enhance clinical efficacy. This study evaluated the efficacy of antiacne dermocosmetic products in treating mild to moderate acne. Methods This open‐label study included Asian patients aged ≥ 14 years with mild to moderate acne. These patients were asked to apply a facial cleanser and cream containing dermocosmetic ingredients twice daily for 3 months; they were allowed to use other antiacne medications except for isotretinoin. The primary outcome was changes in acne severity, and the secondary outcomes were acne‐related complications, skin sensitivity, and patient‐reported stigmatization. Results A total of 39 Asian patients with a mean age of 28.3 years were included. Of these patients, 20.5% were concurrently receiving other antiacne treatments. Most of the patients had only facial acne. The patients’ Global Evaluation Acne score for facial acnes decreased significantly from 2.17 ± 0.81 at baseline to 1.11 ± 0.71 after 3 months of treatment (mean ± standard deviation). A similar reduction was observed in subgroups receiving monotherapy and those receiving treatment with dermocosmetics as an adjunct to medication. Additionally, the severity of complications, including scarring and skin discoloration, decreased. Patient‐reported outcomes revealed major improvements in mental and social well‐being. The investigators and the patients reported high product tolerance and expressed high overall satisfaction with the outcomes. Conclusion Dermocosmetics can reduce acne severity and improve the overall well‐being of Asian patients with acne.