Assessment of the Antimicrobial Inclusion Complex of Four Essential Oils in β-Cyclodextrin

By creating inclusion complexes with β-CD, the effort aims to increase the stability and release of four plant essential oils: camellia, lemon, laurel, and litsea cubeba. It is obvious from the antibacterial experiment that β-CD is the ideal wall material for CAEO to regulate the essential oils’ delayed release and increase the antibacterial activity’s duration. Studies on release kinetics show that the essential oil microcapsules’ release behaviour at 37°C and 65°C follows the Peppas equation, indicating a non-Fickian diffusion mechanism. In conclusion, β-CD can be used as a wall volume to control the constant flow of essential oils and extend the persistence of the antibacterial effect.