This research investigates how different antigen sources affect the development of intestinal Treg cells.
Examined the reactivity of various antigens
Analyzed the roles of antigen-presenting cell subsets
Investigated the impact of diet and microbiota on Treg biology.
Identified multiple sources of antigens influencing Treg cells
Demonstrated the interplay between diet, microbiota, and antigen response
Outlined the need for future studies on antigen-presenting cell functions.
Abstract
antigen reactivity, and we highlight key future directions for elucidating the functional roles of antigen-presenting cell subsets and their associated peptide landscapes in shaping intestinal Treg biology.