Enhancing Biosafety and Reduction of Injuries in Research Laboratories Through Implementation of Safer Sharps Controls

Introduction: Sharps safety is critical in preventing injuries such as cuts, lacerations, and needlestick wounds, particularly in research environments where sharp instruments are frequently used and there is a risk of exposure to biological hazards. The aim of this study was to assess how effectively implemented control measures reduce sharp-related injuries in research environments. This study examines the implementation of best practices aimed at preventing sharp-related injuries in research settings through a combination of substitution, engineering controls, administrative controls, and employee education via workshops and training. Methods: The Abigail Wexner Research Institute (AWRI) adopted a multi-faceted safety program focused on equipment redesign, engineering controls, staff education, and engagement. Injury data from 2019 through 2025 were analyzed to evaluate the development and impact of targeted initiatives. Initiatives included implementation of a revised cryostat/microtome policy, hands-on workshops, and provision of safer engineering controls or alternatives. Results: A 35% reduction in overall sharps injuries was observed from 2022 to 2023 (from 20 to 13 incidents), alongside a 70% drop in Occupational Safety and Health Administration (OSHA)-recordable injuries (from 10 to 3 incidents). From 2024 to 2025, a 28% reduction in overall sharps injuries was observed (from 21 to 15 incidents), alongside a 67% reduction in OSHA-recordable injuries (from 3 to 1 incidents). Notably, injuries related to cryostats and microtomes dropped to zero in 2023. Conclusion: Implementation of targeted, comprehensive sharps safety initiatives led to significant injury reduction at AWRI. This demonstrates the effectiveness of combining administrative policy, training, and equipment improvements in fostering a culture of safety.