Key result
Electron-beam CT regurgitation fractions correlated well with echocardiographic grading (r=0.82, P<0.05), but semiquantitative classification mismatched by at least one grade in >33% of patients.
Why the study?
Does electron-beam CT accurately quantify mitral valve regurgitation compared to Doppler echocardiography and MRI in patients with known or suspected mitral valve regurgitation?
Population
219 patients, including 157 with known isolated mitral valve regurgitation.
Comparison
Electron-beam computed tomography for volume and… vs Doppler echocardiography and magnetic resonance…
Design
Cross-sectional
Authors
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Caution against semiquantitative mitral regurgitation grading by electron-beam CT; leaves open quantitative validation versus echocardiography and MRI.
Observational (n=219)
Does electron-beam CT accurately quantify mitral valve regurgitation compared to Doppler echocardiography and MRI in patients with known or suspected mitral valve regurgitation?
Effect estimate: r(S) = 0.82
p-value: p=< .05
Electron-beam CT provides quantitative information on mitral valve regurgitation severity that correlates well with echocardiography, but semiquantitative classification shows frequent mismatches of at least one grade.
Lembcke et al. (2005) conducted an observational in Mitral valve regurgitation (n=219). Electron-beam computed tomography (CT) vs. Doppler echocardiography and magnetic resonance (MR) imaging was evaluated on Correlation of mitral valve regurgitation fractions calculated at electron-beam CT with echocardiographic grades (r(S) = 0.82, p=< .05). Electron-beam CT regurgitation fractions correlated well with echocardiographic grading (r=0.82, P<0.05), but semiquantitative classification mismatched by at least one grade in >33% of patients.
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