Malay ethnicity was associated with the highest 3.1-year case-fatality following myocardial infarction compared with Chinese ethnicity (HR 1.26; 95% CI 1.14-1.38).
Observational (n=12,481)
Yes
Are there ethnic differences in MI event and mortality rates among Chinese, Malay, and Indian residents of Singapore?
There are significant ethnic disparities in MI incidence and mortality in Singapore, with Indians having the highest event rates and Malays having the highest case-fatality.
Effect estimate: HR 1.26 (95% CI 1.14-1.38)
AIMS: We compare the myocardial infarction (MI) event and mortality rates among Chinese, Malay and Indian residents of Singapore. METHODS: Residents, aged 20 to 64 years, with an MI event were identified from hospital discharge listings, postmortem reports, and the Registry of Births and Deaths. All pathology laboratories flagged patients with elevated creatine phosphokinase (CPK) levels. Modified MONICA (multinational monitoring of trends and determinants in cardiovascular disease) criteria were used for determining MI events. RESULTS: From 1991 to 1999, 12 481 MI events were identified. Chinese patients were older and less likely to have typical symptoms or previous MI. Malays had the highest peak CPK level. Among all three ethnic groups, MI event and age-adjusted case-fatality rates declined. Compared with Chinese, MI event rates were >2-fold and >3-fold higher, and age-standardized coronary mortality rates were 2.4 and 3.0 higher times for Malays and Indians, respectively. Malays have the highest 3.1-year case-fatality, with an adjusted hazard ratio of 1.26 (95% confidence interval, 1.14 to 1.38) compared with Chinese. CONCLUSION: We found strong ethnic differences in MI event, case-fatality and coronary mortality rates among the three ethnic groups in Singapore. While Indians have the greatest MI event rates, Malays have the highest case-fatality.
K.-H. Mak (Wed,) conducted a observational in Acute myocardial infarction (n=12,481). Malay and Indian ethnicity vs. Chinese ethnicity was evaluated on 3.1-year case-fatality (HR 1.26, 95% CI 1.14-1.38). Malay ethnicity was associated with the highest 3.1-year case-fatality following myocardial infarction compared with Chinese ethnicity (HR 1.26; 95% CI 1.14-1.38).