Key result
Cardioneuroablation extended to the posteromedial left ganglionated plexus shows 0 recurrent events at 4 months.
Why the study?
Cardioneuroablation modulates cardiac parasympathetic tone in vagally mediated syncope, and the authors describe a patient who developed AV block following an initial procedure requiring a second ablation.
Does cardioneuroablation targeting the posteromedial left ganglionated plexus prevent recurrent syncope in a patient with vagally mediated syncope?
Population
A 47-year-old man with recurrent vagally mediated syncope, sinus bradycardia, and sinus arrest pauses up to 17 seconds
Comparison
Second cardioneuroablation targeting posteromedial left GP after initial right superior and posterior GP ablation
Design
Case report
Follow-up
4 months
Authors
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Extending ablation to posteromedial left GP merits consideration in refractory cases; hypothesis-generating, requiring prospective trials.
Case Report (n=1)
Does cardioneuroablation targeting the posteromedial left ganglionated plexus prevent recurrent syncope in a patient with vagally mediated syncope?
Ablation limited to the right superior and posterior GPs may be insufficient for neurocardiogenic syncope, and extending ablation to the posteromedial left GP should be considered.
Ascione et al. (2022) conducted a case report in Neurocardiogenic syncope (n=1). Cardioneuroablation targeting the posteromedial left ganglionated plexus was evaluated on Recurrent syncopal events and bradyarrhythmia episodes. Cardioneuroablation extended to the posteromedial left ganglionated plexus resulted in 0 recurrent syncopal events and bradyarrhythmias at 4 months.
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