Key result
Targeting autonomic elements at specific sites on the heart, such as ganglionated plexi, may suppress atrial fibrillation while reducing extensive damage to healthy myocardium.
Why the study?
Does ablation targeting autonomic nerves and ganglionated plexi suppress atrial fibrillation?
Does ablation targeting autonomic nerves and ganglionated plexi suppress atrial fibrillation?
Targeting intrinsic cardiac ganglia, specifically ganglionated plexi at pulmonary vein entrances, represents a promising ablation strategy for atrial fibrillation that may reduce extensive damage to healthy myocardium.
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May support targeted ganglionated plexi ablation to limit myocardial injury in AF; leaves open confirmation via randomized trials.
Scherlag et al. (2005) conducted a review in Atrial fibrillation. Targeting autonomic nerves and ganglia (ablation of ganglionated plexi) was evaluated. Targeting autonomic elements at specific sites on the heart, such as ganglionated plexi, may suppress atrial fibrillation while reducing extensive damage to healthy myocardium.
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