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April 1, 1993Biochemistry

Phosphatidylinositol 3-kinase p85 SH2 domain specificity defined by direct phosphopeptide/SH2 domain binding

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Authors

EPE. PiccioneJoslin Diabetes CenterRCRandi D. CaseJoslin Diabetes CenterSDSusan M. DomchekThe Wistar Institute

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Piccione et al. (1993) studied this question.

synapsesocial.com/papers/6a16a79b83b2be9fec6b5241https://doi.org/10.1021/bi00064a001
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A photoaffinity scan maps regions of the p85 SH2 domain involved in phosphoprotein binding.1993 · 42 citations
  2. 2Alternative Strategies for the Fmoc Solid‐Phase Synthesis of <i>O</i><sup>4</sup>‐Phospho‐L‐tyrosine‐Containing Peptides1991 · 121 citations
  3. 3Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo.1992 · 291 citations
  4. 4Secondary structure of Src homology 2 domain of c-Abl by heteronuclear NMR spectroscopy in solution.1992 · 39 citations
  5. 5Polyoma virus middle T antigen-pp60c-src complex associates with purified phosphatidylinositol 3-kinase in vitro.1992 · 79 citations