Key result
Oral contraceptive use in female smokers was associated with greater blood pressure and total peripheral resistance increases in response to acute smoking and stress compared to non-users.
Why the study?
Does oral contraceptive use alter cardiovascular, lipid, and fibrinogen responses to acute smoking and stress in women?
Population
52 female smokers and nonsmokers
Comparison
Oral contraceptive use, combined with acute… vs No oral contraceptive use
Authors
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May warrant caution combining OCs with smoking; leaves open causal confirmation and practice implications.
Cross-Sectional (n=52)
Does oral contraceptive use alter cardiovascular, lipid, and fibrinogen responses to acute smoking and stress in women?
Oral contraceptive use enhances vascular responsivity to smoking combined with stress, providing a physiological basis for the increased cardiovascular risk observed in women who smoke and use oral contraceptives.
Mary C. Davis (1999) conducted a cross-sectional in Healthy female smokers and nonsmokers (n=52). Acute smoking and oral contraceptive use vs. Sham-smoking and no oral contraceptive use was evaluated on Cardiovascular, lipid, and fibrinogen stress responses. Oral contraceptive use in female smokers was associated with greater blood pressure and total peripheral resistance increases in response to acute smoking and stress compared to non-users.
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