Why the study?
Does cigarette smoking increase the risk of hospitalization for acute myocardial infarction in women?
Does cigarette smoking increase the risk of hospitalization for acute myocardial infarction in women?
Cigarette smoking is associated with a three-fold increased risk of non-fatal myocardial infarction in women, a risk that normalizes to that of never-smokers upon smoking cessation.
Answers are grounded in this paper and cite their sources.
Alerts clinicians to independent MI risk from smoking in women; leaves open prospective confirmation and generalizability beyond case-control data.
The relationship between smoking and the risk of hospitalization for acute myocardial infarction (MI) was evaluated among 121,964 nurses and aged 30-55 years who resided in 11 of the larger US states and who responded to a mail questionnaire. Among 249 women who experienced an MI, 159 (64%) were smokers at the time of hospitalization. Of 4977 controls matched to the cases on the basis of age, 1850 (37%) were smoking at the corresponding time. Smokers experienced a three-fold increase in risk of MI relative to individuals who never smoked, which was not explained by history of hypertension, diabetes, high cholesterol or familial MI. Women who had stopped smoking experienced a risk of MI no greater than women who had never smoked.
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Willett et al. (1981) studied this question.
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