Key result
Review outlines pathogenesis, genetic diagnostics, and current therapies for primary and secondary hypertriglyceridemia.
Why the study?
Hypertriglyceridemias represent a heterogeneous group of pathologies that differ in mechanisms of triglyceride-rich lipoprotein elevation, lipoprotein composition, and related risks.
This review provides an overview of the pathogenesis, diagnosis, and management of primary and secondary hypertriglyceridemias.
Informs hypertriglyceridemia management options; leaves open prospective validation of genetic diagnostics and novel therapies.
Hypertriglyceridemias are a heterogeneous group of pathologies differing in the mechanisms of triglyceride-rich lipoprotein increase, the composition of lipoproteins and related risks. This review article presents information on the profile and pathogenesis of various primary and secondary hypertriglyceridemias, as well as describes current potential of genetic diagnostics, drug and non-drug correction.
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Семенкин et al. (2025) conducted a review in Hypertriglyceridemia. This review summarizes the pathogenesis, genetic diagnostics, and current drug and non-drug treatment options for primary and secondary hypertriglyceridemias.
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