Key result
Review details hypertriglyceridemia pathogenesis and diagnosis while highlighting its link to CVD and acute pancreatitis.
Why the study?
Elevated blood levels of triglyceride-rich particles carry an independent risk of atherosclerotic cardiovascular diseases and acute pancreatitis, warranting a detailed review of pathogenesis, classification, diagnosis, and therapy.
This review provides a comprehensive overview of the risks, pathophysiology, classification, and diagnosis of hypertriglyceridemia, emphasizing its role in cardiovascular disease and pancreatitis.
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Alerts clinicians to hypertriglyceridemia risks in CVD and pancreatitis; leaves open need for updated management trials.
Numerous studies demonstrate an independent relationship between an increase in the blood content of triglyceride-rich particles and the risk of atherosclerotic cardiovascular diseases and acute pancreatitis. This review article presents in detail aspects of the pathogenesis of various types of primary and most relevant secondary hypertriglyceridemias (HTGs). Classifications are provided depending on the etiology, phenotype of dyslipidemia and severity. Approaches to HTG diagnosis are described. Special attention is paid to the potential of HTG therapy.
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Семенкин et al. (2024) conducted a review in Hypertriglyceridemia. This review details the pathogenesis, classification, and diagnosis of primary and secondary hypertriglyceridemias, highlighting their link to cardiovascular disease and acute pancreatitis.
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