Key result
High occupational physical activity was associated with higher all-cause mortality in men compared to low activity (HR 1.25; 95% CI 1.05-1.50), with inconsistent results for women.
Why the study?
Research regarding the effects of occupational physical activity on health remains inconsistent.
Does high occupational physical activity affect all-cause and cardiovascular disease mortality?
Cohort (n=10,176)
Does high occupational physical activity affect all-cause and cardiovascular disease mortality?
Effect estimate: HR 1.25 (95% CI 1.05-1.50)
Higher occupational physical activity is associated with increased all-cause and cardiovascular mortality in men, suggesting that occupational physical activity may not confer the same cardiovascular benefits as leisure-time physical activity.
Questions equivalence of occupational and leisure physical activity for mortality benefit; extends domain-specific observations but remains hypothesis-generating.
BACKGROUND: Research regarding the effects of occupational physical activity on health remains inconsistent. We analyzed the association of occupational physical activity with all-cause and cardiovascular disease (CVD) mortality. METHODS: We analyzed two cohorts with baseline assessments from 1977 to 1993 ("National Research Program 1A" (NRP1A) and "MONItoring of trends and determinants in CArdiovascular disease" [MONICA]) and mortality follow-up until 2015 using adjusted Cox regression models. RESULTS: We included 4396 NRP1A participants (137 793 person-years of follow-up, 1541 deaths) and 5780 MONICA participants (135 410 person-years, 1158 deaths). All-cause mortality was higher for men in the high compared with the low occupational physical activity category according to NRP1A (hazard ratio [HR] 1.25, 95% confidence intervals [CI] 1.05-1.50). CVD mortality was higher for men in the moderate compared with the low occupational physical activity category according to MONICA (HR, 1.41; 95% CI, 1.03-1.91). Results for women were not statistically significant. CONCLUSIONS: We observed higher total and CVD mortality risks in men with higher occupational physical activity but inconsistent results for women and across cohorts.
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Wanner et al. (2019) conducted a cohort in All-cause and cardiovascular disease mortality (n=10,176). High occupational physical activity vs. Low occupational physical activity was evaluated on All-cause mortality (HR 1.25, 95% CI 1.05-1.50). High occupational physical activity was associated with higher all-cause mortality in men compared to low activity (HR 1.25; 95% CI 1.05-1.50), with inconsistent results for women.
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