Key result
Neuroimaging literature suggests that impairment within the cortico-striatal network, involved in effort-reward calculation, is critically related to cognitive fatigue in neurological populations.
Neuroimaging studies suggest that cognitive fatigue in neurological conditions is critically related to impairment within the cortico-striatal network involved in effort-reward calculation.
Supports neuroimaging evaluation of cortico-striatal impairment in cognitive fatigue; leaves open prospective validation before practice change.
Recently, there has been renewed interest in the study of cognitive fatigue. It is known that fatigue is one of the most disabling symptoms in numerous neurological populations, including stroke, multiple sclerosis, Parkinson’s disease, and traumatic brain injury. Behavioral studies of cognitive fatigue are hampered by lack of correlation of self-report measures with objective performance. Neuroimaging studies provide new insight about cognitive fatigue and its neural correlates.Impairment within the cortico-striatal network, involved in effort–reward calculation, has been suggested to be critically related to fatigue. The current review surveys the recent neuroimaging literature, and suggests promising avenues for future research.
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Dobryakova et al. (2013) conducted a review in Cognitive fatigue. Neuroimaging literature suggests that impairment within the cortico-striatal network, involved in effort-reward calculation, is critically related to cognitive fatigue in neurological populations.
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