Key result
New hypertension in young patients is associated with ~96% higher depression and anxiety scores.
Why the study?
Although psychological stress like anxiety and depression may trigger hypertension via increased sympathetic activity, their relationship remains unclear, especially in newly diagnosed young hypertensive patients.
Case-Control (n=300)
No
Young patients with newly diagnosed hypertension have significantly higher rates of depression and anxiety, suggesting psychological stress may be an important trigger or comorbidity to address in early hypertension management.
Answers are grounded in this paper and cite their sources.
May warrant mood screening in young hypertensives; hypothesis-generating for causality, needs prospective validation.
Aim: Hypertension (HT) is a very important risk factor for cerebrovascular, renal and various vascular diseases, especially cardiovascular diseases. It is seen in almost 1/3 of the adult world population and its incidence is gradually increasing. 95% of HT is essential and various reasons are emphasized in the etiology. Conditions that cause psychological stress, especially depression; Although the relationship between them is not clear, it was seen as a risk factor for HT. Because they will live with HT for a long time, early diagnosis and treatment is important, especially in young patients. Predisposing factors should also be taken into account in treatment. Anxiety and depression, which are called increased sympathetic activity in young people, can be a trigger for HT. In this study, we wanted to investigate the susceptibility to depressionanxiety in newly diagnosed young hypertensive patients. According to the result, we thought that we could make new recommendations in the treatment of HT. Materials and Methods: 175 patients under the age of 45 with newly diagnosed HT and 125 individuals under 45 without any health problems were included in the study. Those diagnosed with HT with secondary reasons and those with chronic diseases such as coronary artery disease (CAD), diabetes mellitus (DM), chronic renal failure (CRF), congestive heart failure (CHF) were excluded from the study. Testing was performed with the Hospital Depression Anxiety Scale (HDAS). In this test for both anxiety and depression; 0-7 points were considered normal, 8-10 points were considered borderline, and over 11 points were considered abnormal. Results: When the results were evaluated, there was no difference between the groups in terms of age, gender, and routine biochemical tests. Both depression and anxiety scales were found to be significantly higher in the HT group. In young hypertensive patients, we have seen that HT and depression-anxiety frequently coexist. Conclusion: In this case, we should definitely examine the psychological stress states of young patients we diagnosed with HT. It would be appropriate to refer patients who we think may have depression and anxiety for psychological support and treatment. When psychological problems are treated, HT may improve without the need for antihypertensive treatment. Thus, we can develop new approaches in HT treatment.
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Kuzeytemiz et al. (2022) conducted a case-control in Hypertension (n=300). Hypertension vs. Healthy individuals without hypertension was evaluated on HADS depression score (p=<0.001). Newly diagnosed young hypertensive patients had significantly higher mean depression (10.86 vs 5.55) and anxiety (10.26 vs 5.63) scores compared to healthy controls.
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