Key result
Modified double root translocation for complete transposition of great arteries with left ventricular outflow tract obstruction resulted in recovery and hospital discharge for 5 out of 6 patients.
Why the study?
Does modified double root translocation improve outcomes in pediatric patients with complete transposition of great arteries with left ventricular outflow tract obstruction?
Observational (n=6)
Does modified double root translocation improve outcomes in pediatric patients with complete transposition of great arteries with left ventricular outflow tract obstruction?
Answers are grounded in this paper and cite their sources.
Modified double root translocation appears to be an effective surgical option for managing complete transposition of great arteries with left ventricular outflow tract obstruction, yielding good short-to-medium term outcomes in survivors.
To summarize the therapeutic effects of modified double root translocation (MDRT) in the management of congenital heart disease-transposition of great arteries (TGA) with ventricular septum defect (VSD) and left ventricular outflow tract obstruction (LVOTO). From May 2013 to March 2015, we treated 6 patients (4 males, 2 females, aged from 1 year and 8 months old to 5 years old) with complete transposition of great arteries with left ventricular outflow tract obstruction, SaO2 54 ± 7.3%; the outflow velocity of the left ventricular or pulmonary valve measured by Doppler was 4.46 ± 0.15 m/s, and the Nakata index was 217 ± 32 cm(2)/m(2). We carried out a double root translocation operation on these 6 patients.One patient developed low cardiac output syndrome 4 hours after the operation. Extracorporeal membrane oxygenation (ECMO) was performed, but the patient died of multiple organ failure. The other 5 patients all recovered and were discharged from the hospital. During the 3-month to 2-year follow-up period, these 5 patients all demonstrated NYHA Class I or NYHA Class II LVEF (65 ± 2.7) %; 4 had mild pulmonary regurgitation, 1 moderate pulmonary regurgitation; 3 no aortic regurgitation, and 2 micro aortic regurgitation, SaO2 99 ± 0.4%.Modified double root translocation is an effective treatment method in the management of complete transposition of great arteries with left ventricular outflow tract obstruction.
No takes yet. Share an insight, caveat, or question.
Yang et al. (2016) conducted an observational in Complete transposition of great arteries with ventricular septum defect and left ventricular outflow tract obstruction (n=6). Modified double root translocation (MDRT) was evaluated on Recovery and post-operative cardiac function. Modified double root translocation for complete transposition of great arteries with left ventricular outflow tract obstruction resulted in recovery and hospital discharge for 5 out of 6 patients.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: