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September 1, 1986HeartOpen Access

Anatomical correction of transposition of the great arteries and Taussig-Bing anomaly resulted in no late deaths, though mean ejection fraction was lower in complex versus simple transposition (62% vs 77%).

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Why the study?

What are the intermediate functional results after anatomical correction of transposition of the great arteries and Taussig-Bing anomaly?

Population

33 patients after anatomical correction of transposition of the great arteries or double outlet right…

Design

Cohort

Follow-up

two weeks to 44 months

Key result

Anatomical correction of transposition of the great arteries and Taussig-Bing anomaly resulted in no late deaths, though mean ejection fraction was lower in complex versus simple transposition (62% vs 77%).

Authors

CLChristopher LincolnARAndrew N. RedingtonKLK Li

Discussion

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Overview

Supports good intermediate survival after anatomical correction of transposition; leaves open the significance of reduced ejection fraction in complex cases.

Study Design

Type

Cohort (n=33)

Structured PICO

What are the intermediate functional results after anatomical correction of transposition of the great arteries and Taussig-Bing anomaly?

P
Population
33 patients followed up after anatomical correction of transposition of the great arteries or Taussig-Bing anomaly, with 17 undergoing cardiac catheterisation 2 weeks to 44 months post-operation.
E
Exposure
Anatomical correction (surgery)
O
Outcome
Intermediate functional results including clinical progress, late deaths, and cardiac catheterisation findings (right ventricular outflow tract gradients, valvar regurgitation, coronary patency, and left ventricular function)surrogate

Main Result

Absolute Event Rate: 62% vs 77%

Anatomical correction of transposition of the great arteries and Taussig-Bing anomaly yields satisfactory intermediate anatomical and functional results, though some patients exhibit left ventricular wall motion abnormalities of unknown implication.

Limitations

  • The implications of the left ventricular wall motion abnormalities is unknown.

Cite This Study

Lincoln et al. (1986) conducted a cohort in Transposition of the great arteries or double outlet right ventricle and subpulmonary ventricular septal defect (Taussig-Bing anomaly) (n=33). Anatomical correction vs. Simple vs complex transposition (for subgroup analysis) was evaluated on Left ventricular ejection fraction. Anatomical correction of transposition of the great arteries and Taussig-Bing anomaly resulted in no late deaths, though mean ejection fraction was lower in complex versus simple transposition (62% vs 77%).

synapsesocial.com/papers/6a9e4f6da2ccee6cb1da2cdchttps://doi.org/10.1136/hrt.56.3.259
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