Key result
Men exhibit a greater BP pressor response to spontaneous K-complexes during sleep than women.
Why the study?
K-complexes during stage II sleep elicit acute increases in blood pressure and heart rate, but the role of sex in this response is unclear.
Does sex influence blood pressure responsiveness to spontaneous K-complexes during stage II sleep?
Observational
Does sex influence blood pressure responsiveness to spontaneous K-complexes during stage II sleep?
Men exhibit an augmented blood pressure response to spontaneous K-complexes during stage II sleep compared to women, highlighting a sex difference in nocturnal blood pressure control.
Sex differences in BP reactivity to K-complexes may reflect nocturnal autonomic variation; hypothesis-generating and should not yet change practice.
K-complexes during stage II sleep have been shown to elicit acute increases in blood pressure and heart rate, but the role of sex (i.e., male vs. female) in this response is unclear. In the present study, we demonstrate that the pressor response following spontaneous K-complexes were augmented in men compared to age-matched women. The augmented blood pressure reactivity to spontaneous K-complexes during stage II sleep in men advance the field of cardiovascular sex differences, with implications for nocturnal blood pressure control.
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Greenlund et al. (2020) conducted an observational in Stage II sleep. Male sex vs. Female sex was evaluated on Pressor response following spontaneous K-complexes. Men exhibited an augmented blood pressure pressor response following spontaneous K-complexes during stage II sleep compared to age-matched women.
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