Key result
Cognitive stimulation improves cognition in moderate Alzheimer's disease, but effects fade by three months.
Why the study?
Cognitive stimulation is a recommended non-pharmacological therapy for dementia, but its efficacy needed evaluation in people with moderate Alzheimer's disease.
Does cognitive stimulation improve memory, attention, and executive functions in people with moderate Alzheimer's disease?
RCT (n=71)
Randomly assigned
Does cognitive stimulation improve memory, attention, and executive functions in people with moderate Alzheimer's disease?
Cognitive stimulation provides short-term improvements in cognitive domains for patients with moderate Alzheimer's disease, but these benefits diminish by 3 months.
Answers are grounded in this paper and cite their sources.
May support short-term cognitive stimulation in moderate Alzheimer's; extends RCT evidence on non-pharmacological approaches but highlights durability gaps.
Cognitive stimulation is one of the non-pharmacological therapies recommended for dementia intervention. The present study evaluated the efficacy of an intervention based on cognitive stimulation in people with moderate Alzheimer’s disease. Fifty-nine subjects with moderate dementia were randomly assigned to the stimulation group ( N = 36) and the control group ( N = 35). The treatment group received 16 intervention sessions cognitive tasks. All participants were evaluated with a battery of neuropsychological tests at three time points (pre, post, and follow-up). The treatment group showed significant increases in the three domains studied (memory, attention, and executive functions), although some of these effects were not maintained at follow-up. The control group progressively worsened. Cognitive stimulation was found to be an effective intervention for people with moderate Alzheimer’s disease because it helped to maintain memory function, executive functions, and attention. However, the effects were minimized at the 3-month follow-up.
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González-Moreno et al. (2022) conducted an RCT in Moderate Alzheimer's disease (n=71). Cognitive stimulation vs. Control group was evaluated on Memory, attention, and executive functions. Cognitive stimulation significantly improved memory, attention, and executive functions in patients with moderate Alzheimer's disease, though effects were minimized at 3-month follow-up.
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