Key result
Strict rate control to a resting heart rate below 80 bpm in patients with chronic atrial fibrillation significantly reduced B-type natriuretic peptide levels and cardiac chamber volumes.
Why the study?
Does strict rate control improve B-type natriuretic peptide values and echocardiographic parameters of cardiac remodeling in patients with chronic atrial fibrillation?
Observational (n=38)
Single-blind
No
Does strict rate control improve B-type natriuretic peptide values and echocardiographic parameters of cardiac remodeling in patients with chronic atrial fibrillation?
Absolute Event Rate: -143.8% vs 124.5%
p-value: p=< 0.001
Achieving strict rate control (<80 bpm) in chronic atrial fibrillation is associated with significant reductions in BNP levels and reverse cardiac remodeling compared to lenient rate control.
No takes yet. Share an insight, caveat, or question.
Should not yet change rate control practice in chronic AF; hypothesis-generating for remodeling effects and requires randomized confirmation.
Özkurt et al. (2014) conducted an observational in Chronic atrial fibrillation (n=38). Strict rate control (resting HR < 80 bpm) vs. Lenient rate control (resting HR > 80 bpm) was evaluated on Change in B-type natriuretic peptide (BNP) levels (pg/dL) (p=< 0.001). Strict rate control to a resting heart rate below 80 bpm in patients with chronic atrial fibrillation significantly reduced B-type natriuretic peptide levels and cardiac chamber volumes.
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