Key result
Malnutrition linked to ~566% higher long-term mortality following VT ablation.
Why the study?
Although obesity and malnutrition are linked to adverse events in structural heart disease, their impact on procedural and post-procedural midterm outcomes after ventricular tachycardia ablation was unknown.
Does malnutrition or obesity affect procedural and midterm outcomes in patients with structural heart disease undergoing ventricular tachycardia ablation?
Observational (n=203)
No
Does malnutrition or obesity affect procedural and midterm outcomes in patients with structural heart disease undergoing ventricular tachycardia ablation?
Effect estimate: HR 6.659 (95% CI 2.553-17.369)
Absolute Event Rate: 50% vs 7%
p-value: p=<0.001
Malnutrition, as assessed by the Prognostic Nutritional Index, is a strong independent predictor of long-term mortality in patients with structural heart disease undergoing VT ablation, whereas obesity defined by BMI does not significantly impact outcomes.
Malnutrition screening may refine pre-ablation risk stratification; leaves open whether intervention improves survival in this observational cohort.
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Baskovski et al. (2025) conducted an observational in Structural heart disease with ventricular tachycardia (n=203). Malnutrition (Prognostic Nutritional Index < 38) vs. Non-malnourished (Prognostic Nutritional Index ≥ 38) was evaluated on Mortality during follow-up (HR 6.659, 95% CI 2.553-17.369, p=<0.001). Malnutrition, defined by a Prognostic Nutritional Index < 38, significantly increased long-term mortality (HR 6.659) compared to non-malnourished patients following ventricular tachycardia ablation.
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