Key result
Comorbid COPD in patients with atrial fibrillation was associated with significantly higher all-cause mortality (28.3% vs 15.5%; P<0.001) and hemorrhagic events (3.3% vs 1.9%; P=0.004).
Why the study?
Patients with COPD are at higher risk of AF, but information regarding clinical outcomes and optimal medical treatment of AF in the setting of COPD remains missing.
Does comorbid COPD increase mortality and adverse events in patients with atrial fibrillation?
Cohort (n=7,990)
Does comorbid COPD increase mortality and adverse events in patients with atrial fibrillation?
Absolute Event Rate: 28.3% vs 15.5%
p-value: p=<0.001
Comorbid COPD in atrial fibrillation patients is associated with significantly increased all-cause mortality and hemorrhagic events, highlighting the need for optimized medical therapy including oral anticoagulation and beta-blockers.
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Comorbid COPD may identify higher-risk AF subgroup; extends observational data but leaves open intervention effects.
Rodríguez‐Mañero et al. (2019) conducted a cohort in Atrial fibrillation (n=7,990). Comorbid COPD vs. No COPD was evaluated on All-cause mortality (p=<0.001). Comorbid COPD in patients with atrial fibrillation was associated with significantly higher all-cause mortality (28.3% vs 15.5%; P<0.001) and hemorrhagic events (3.3% vs 1.9%; P=0.004).
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