Key result
Long-term depression duration was significantly longer in stroke patients compared to healthy controls (p<0.001), despite similar overall depression prevalence (18.2% vs 24.0%, p>0.05).
Why the study?
Is long-term depression associated with an increased risk of stroke?
Case-Control (n=248)
Is long-term depression associated with an increased risk of stroke?
Long-term depression is associated with an increased risk of stroke, suggesting that depression duration is a relevant risk factor.
Depression duration may identify elevated stroke risk; leaves open causality and requires prospective confirmation.
Kocer E, Kocer A, Degirmenci Y, Eryılmaz M. Long-term depression is a stroke risk factor. Background and Aim: Only a few studies have evaluated depression prevalence in pre-stroke period in comparison to controls. We investigated this association based on a hospitalised stroke population. Methods: One hundred and forty-eight stroke patients were evaluated. The presence of depression was compared with those of 100 healthy controls without stroke, from the same region. Depression was accepted as present or not present after history and clinical evaluation according to Diagnostic and Statistical Manual of Mental Disorders-IV. Socio-demographic variables, other stroke risk factors and the time of diagnosis of depression (how many year or month they got depression) were recorded. Results: Gender and mean age of patients and controls were similar in comparison. Depression was diagnosed in 27 patients and 24 controls ( p > 0.05). The time period passed after diagnosis of depression was longer in stroke patients in comparison to controls ( p < 0.001). Conclusions: The risk of stroke should be considered in elderly with long-term depression. This indicates that treatment of depression is another factor which should be considered in prevention of brain stroke.
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Koçer et al. (2011) conducted a case-control in Stroke (n=248). Depression vs. Healthy controls was evaluated on Prevalence of depression (p=>0.05). Long-term depression duration was significantly longer in stroke patients compared to healthy controls (p<0.001), despite similar overall depression prevalence (18.2% vs 24.0%, p>0.05).
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