Lifestyle modification programmes for patients with coronary heart disease: a systematic review and meta-analysis of randomized controlled trials
Key result
Lifestyle modification programmes for coronary heart disease patients reduced all-cause mortality (OR 1.34; 95% CI 1.10-1.64) compared to routine clinical care.
Why the study?
Do lifestyle modification programmes reduce mortality and cardiac events in patients with coronary heart disease?
Population
11,085 randomized patients with coronary heart disease from 23 trials
Comparison
Lifestyle modification programmes developed… vs Routine clinical care alone
Design
Meta-analysis
Follow-up
Mean 10.2 months posttreatment, long-term mean 33.7 months
Authors
Discussion
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Member takes
Implication
Supports integrating lifestyle modification programmes into coronary heart disease care; confirms mortality reduction in Level 1 evidence.
Study Design
Type
Meta-Analysis (n=11,085)
Structured PICO
Do lifestyle modification programmes reduce mortality and cardiac events in patients with coronary heart disease?
P
Population
11,085 randomized patients with coronary heart disease from 23 trials
I
Intervention
Lifestyle modification programmes developed between 1999-2009
C
Comparator
Routine clinical care alone
O
Outcome
All-cause mortality, cardiac mortality, and cardiac readmissions and non-fatal reinfarctionshard clinical
Main Result
Effect estimate: OR 1.34 (95% CI 1.10-1.64)
Lifestyle modification programs significantly reduce all-cause and cardiac mortality, as well as cardiac readmissions and non-fatal reinfarctions, beyond routine clinical care in patients with coronary heart disease.
Cite This Study
Janssen et al. (2012) conducted a meta-analysis in coronary heart disease (n=11,085). Lifestyle modification programmes vs. routine clinical care was evaluated on all-cause mortality (OR 1.34, 95% CI 1.10-1.64). Lifestyle modification programmes for coronary heart disease patients reduced all-cause mortality (OR 1.34; 95% CI 1.10-1.64) compared to routine clinical care.