Key result
Psychologic stress reduced the threshold for repetitive ventricular response in dogs, indicating electrical instability and a predisposition to ventricular fibrillation.
Hypothesis-generating for stress-triggered arrhythmias; leaves open translation from canine models to human sudden death prevention.
A psychologically stressful environment reduced the threshold of the dog's ventricle for repetitive response. Elicitation of such a response indicates the presence of electrical instability and a predisposition to ventricular fibrillation, the mechanism of sudden death.
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Lown et al. (1973) studied this question. Psychologic stress reduced the threshold for repetitive ventricular response in dogs, indicating electrical instability and a predisposition to ventricular fibrillation.
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