Key result
In vivo 3D magnetic resonance elastography detected increased stiffness in infarcted compared to remote myocardium (4.6 ± 0.7 kPa vs 3.0 ± 0.6 kPa, P=0.02) in a porcine model of myocardial infarction.
Why the study?
Can high-frequency 3D cardiac MRE assess in vivo regional myocardial stiffness in a porcine model of myocardial infarction?
Can high-frequency 3D cardiac MRE assess in vivo regional myocardial stiffness in a porcine model of myocardial infarction?
Absolute Event Rate: 4.6% vs 3%
p-value: p=0.02
High-frequency 3D cardiac MRE is a feasible noninvasive method for assessing regional myocardial stiffness in vivo after myocardial infarction.
No takes yet. Share an insight, caveat, or question.
Supports feasibility of 3D MRE for regional stiffness assessment in MI models; leaves open human translation and clinical utility.
Arunachalam et al. (2017) studied Myocardial infarction. 3D magnetic resonance elastography (MRE) vs. Remote myocardium was evaluated on In vivo MRE stiffness (p=0.02). In vivo 3D magnetic resonance elastography detected increased stiffness in infarcted compared to remote myocardium (4.6 ± 0.7 kPa vs 3.0 ± 0.6 kPa, P=0.02) in a porcine model of myocardial infarction.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: