Key result
Persistent atrial fibrillation was associated with more severe depressed mood than paroxysmal AF (adjusted OR 1.44; 95% CI 1.13-1.75; P=0.007), with major depressive disorder in 10.5% vs 5.8%.
Why the study?
Is depressed mood more severe or common in patients with persistent atrial fibrillation compared to those with paroxysmal atrial fibrillation?
Cross-Sectional (n=702)
Is depressed mood more severe or common in patients with persistent atrial fibrillation compared to those with paroxysmal atrial fibrillation?
Effect estimate: OR 1.89 (95% CI 1.07-3.37)
Absolute Event Rate: 10.5% vs 5.8%
Patients with persistent atrial fibrillation experience significantly more severe depressed mood and a higher prevalence of major depressive disorder compared to those with paroxysmal atrial fibrillation.
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Supports depression screening in persistent AF; hypothesis-generating for causality and interventions.
Rothe et al. (2013) conducted a cross-sectional in Atrial fibrillation (n=702). Persistent atrial fibrillation vs. Paroxysmal atrial fibrillation was evaluated on Major depressive disorder (OR 1.89, 95% CI 1.07-3.37). Persistent atrial fibrillation was associated with more severe depressed mood than paroxysmal AF (adjusted OR 1.44; 95% CI 1.13-1.75; P=0.007), with major depressive disorder in 10.5% vs 5.8%.
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