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September 1, 1993StrokeOpen Access

Carotid artery intimal-medial thickness distribution in general populations as evaluated by B-mode ultrasound. ARIC Investigators.

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Why the study?

What is the distribution of carotid artery intimal-medial thickness in the general population as evaluated by B-mode ultrasound?

Population

General population participants in the Atherosclerosis Risk in Communities study, analyzed by race-sex strata.

Design

Cross-sectional

Authors

GHGeorge HowardASA. Richey SharrettGHGerardo Heiss

Discussion

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Overview

Provides normative carotid IMT ranges by age/sex; leaves open their added value for risk stratification in prospective studies.

Key Points

  • This research aims to describe the distribution of carotid artery intimal-medial thickness in the general population using B-mode ultrasound.
  • Used B-mode ultrasound to measure arterial wall thickness in the ARIC study.
  • Analyzed data by race-sex strata with 759 to 4952 individuals imaged depending on location.
  • Examined age-related increases in wall thickness across different carotid artery locations.
  • Median wall thickness ranged from 0.5 to 1 mm; fewer than 5% had values over 2 mm.
  • Larger wall thickness was found at the carotid bifurcation compared to the common carotid artery.
  • Average age-related increases in wall thickness were 0.015 mm/y for women and 0.018 mm/y for men in the carotid bifurcation.

Structured PICO

What is the distribution of carotid artery intimal-medial thickness in the general population as evaluated by B-mode ultrasound?

P
Population
General population participants in the Atherosclerosis Risk in Communities (ARIC) study, analyzed by race-sex strata (759 to 4952 individuals imaged depending on strata and location).
I
Intervention
B-mode real-time ultrasound measurement of extracranial carotid artery intimal-medial thickness
O
Outcome
Distribution of intimal-medial arterial wall thickness in the extracranial carotid arteriessurrogate

This study provides normative estimates for carotid intimal-medial thickness by age, race, and sex in a general population, serving as nomograms for clinical and epidemiological use.

Cite This Study

Howard et al. (1993) studied this question.

synapsesocial.com/papers/6a1767a28008e5848e6e9acbhttps://doi.org/10.1161/01.str.24.9.1297
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