Key result
High anxiety in physically healthy patients was associated with significantly increased crude QT dispersion compared to controls (standardized difference in means 1.472; 95% CI 1.034-1.911).
Why the study?
Does high anxiety increase QT dispersion in physically healthy subjects?
Population
5 studies pooling 580 physically healthy subjects evaluated for anxiety disorders with validated…
Comparison
Anxiety disorders vs Healthy controls without anxiety
Design
Meta-analysis
Authors
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May flag arrhythmia risk in anxious healthy adults; leaves open causality and need for prospective trials.
Meta-Analysis (n=580)
Does high anxiety increase QT dispersion in physically healthy subjects?
Effect estimate: Standardized difference in means 1.472 (95% CI 1.034-1.911)
High anxiety in physically healthy individuals is associated with increased QT dispersion, a potential surrogate marker for ventricular arrhythmia risk.
Igor A. Kelmanson (2013) conducted a meta-analysis in Anxiety (n=580). Anxiety disorders vs. Controls was evaluated on Crude QT dispersion (Standardized difference in means 1.472, 95% CI 1.034-1.911). High anxiety in physically healthy patients was associated with significantly increased crude QT dispersion compared to controls (standardized difference in means 1.472; 95% CI 1.034-1.911).
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