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We address the problem of constructing quantum circuits to implement an arbitrary two-qubit quantum computation. We pursue circuits without ancilla qubits and as small a number of elementary quantum gates as possible. Our lower bound for worst-case optimal two-qubit circuits calls for at least $17$ gates: $15$ one-qubit rotations and $2$ controlled-NOT (CNOT) gates. We also constructively prove a worst-case upper bound of $23$ elementary gates, of which at most four (CNOT gates) entail multiqubit interactions. Our analysis shows that synthesis algorithms suggested in previous work, although more general, entail larger quantum circuits than ours in the special case of two qubits. One such algorithm has a worst case of $61$ gates, of which $18$ may be CNOT gates.
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Bullock et al. (2003) studied this question.
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