Key result
Left atrial vortex size by 4D flow MRI was significantly elevated in paroxysmal atrial fibrillation compared to healthy controls at end early diastole (6.93 vs 3.98 cm3; P=0.001).
Why the study?
Characterization of left atrial hemodynamics in paroxysmal atrial fibrillation may provide valuable insights for thromboembolic risk.
Are 4D flow MRI-derived left atrial vortex size and velocity distributions associated with age and CHA2DS2-VASc risk score in patients with paroxysmal atrial fibrillation?
Observational (n=60)
Are 4D flow MRI-derived left atrial vortex size and velocity distributions associated with age and CHA2DS2-VASc risk score in patients with paroxysmal atrial fibrillation?
Absolute Event Rate: 6.93% vs 3.98%
p-value: p=0.001
4D flow MRI demonstrates that left atrial vortex size is increased in patients with paroxysmal atrial fibrillation and correlates with stroke risk scores, highlighting its potential as a hemodynamic biomarker.
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Left atrial vortex size may mark altered hemodynamics in paroxysmal AF; leaves open incremental value for stroke risk beyond age.
García et al. (2019) conducted an observational in Paroxysmal atrial fibrillation (n=60). 4D flow MRI vs. Healthy controls was evaluated on LA vortex size at end early diastole (p=0.001). Left atrial vortex size by 4D flow MRI was significantly elevated in paroxysmal atrial fibrillation compared to healthy controls at end early diastole (6.93 vs 3.98 cm3; P=0.001).
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