Key result
Anticancer chemotherapy in teenage and young adult cancer survivors can cause late effects that affect quality of life, requiring management by generalists.
This review provides information for generalists on managing the long-term side effects of anticancer chemotherapy in teenage and young adult cancer survivors.
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Generalists may need to monitor late effects in TYA survivors; leaves open need for prospective management trials.
Cancer is the leading cause of disease related death in teenagers and young adults (TYAs) in Western countries. 1 2 In the UK, cancer in TYAs accounts for 9% and 15% of all male and female deaths respectively, and its incidence has risen by 19% since the mid-1990s, leading to 2300 new cases a year between 2011 and 2013. 1 In Japan it accounted for nearly 7000 deaths between 2000 and 2006. 3 TYA cancer survivors are likely to live for many decades but are at risk of late effects of their treatment. This article provides information for generalists on late effects of anticancer chemotherapy (see infographic and supplementary table A) that may affect quality of life. Radiotherapy related effects are not discussed but are summarised elsewhere.
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Ahmad et al. (2016) conducted a review in Cancer. Anticancer chemotherapy was evaluated. Anticancer chemotherapy in teenage and young adult cancer survivors can cause late effects that affect quality of life, requiring management by generalists.
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