Why the study?
Evidence is limited regarding the prevalence and optimal management of pregnancy in individuals with mechanical heart valves, and high-quality data are lacking.
This guideline outlines the complex risk-benefit considerations for anticoagulation in pregnant patients with mechanical heart valves, emphasizing the need for individualized, multidisciplinary care in tertiary centers.
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Requires individualized multidisciplinary care in tertiary centers for pregnant patients with mechanical heart valves; extends prior observational registries on maternal risks.
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Lester et al. (2023) conducted a review in Pregnancy in individuals with mechanical heart valves. Anticoagulant management was evaluated. Anticoagulant management in pregnant individuals with mechanical heart valves requires individualized multidisciplinary care due to high risks, including 9% maternal mortality and 41% severe morbidity.
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