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May 18, 2022Health and Quality of Life OutcomesOpen Access

Predictors of health-related quality of life after cardiac surgery: a systematic review

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Why the study?

Health-related quality of life determines surgical success from the patient perspective, prompting identification of predictors to highlight modifiable targets for intervention after cardiac surgery.

What are the independent predictors of health-related quality of life after cardiac surgery?

Population

41 included studies of adult patients undergoing cardiac surgery

Comparison

Predictors of post-cardiac surgery HRQoL

Design

Systematic review with narrative synthesis

Key result

A systematic review of 41 studies identified 103 independent predictors of health-related quality of life after cardiac surgery, including potentially modifiable factors like BMI, smoking, and depression.

Authors

JSJulie SandersTBTracey BowdenNLNicholas Woolfe Loftus

Discussion

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Overview

Modifiable predictors may guide prehabilitation to optimize HRQoL after cardiac surgery; leaves open need for interventional trials.

Study Design

Type

Systematic Review

Structured PICO

What are the independent predictors of health-related quality of life after cardiac surgery?

P
Population
Adult patients (≥ 18 years of age) undergoing cardiac surgical procedures (predominantly CABG) across 41 included studies.
I
Intervention
Cardiac surgery (predominantly CABG, valve, or combined)
O
Outcome
Predictors of health-related quality of life (HRQoL) after cardiac surgerypatient reported

Potentially modifiable predictors of HRQoL after cardiac surgery, such as BMI, smoking, and depression, represent targets for prehabilitation interventions to improve patient-centered outcomes.

Limitations

  • Methodological heterogeneity of the included studies restricts the ability to make strong conclusions or undertake a meta-analysis.
  • Only English language publications were included.
  • Included studies were limited to those published from 2001.
  • Methodological heterogeneity of the included studies restricts the ability to make strong conclusions or undertake a meta-analysis
  • Only English language publications were included

Cite This Study

Sanders et al. (2022) conducted a systematic review in Cardiac surgery. Cardiac surgery was evaluated on Independent predictors of health-related quality of life (HRQoL). A systematic review of 41 studies identified 103 independent predictors of health-related quality of life after cardiac surgery, including potentially modifiable factors like BMI, smoking, and depression.

synapsesocial.com/papers/6a1789f67afe20c06351e156https://doi.org/10.1186/s12955-022-01980-4
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