Key result
Coronary artery bypass graft surgery significantly improved the SF-36 Physical Component Summary score at 10 years compared to baseline (59.5 vs 51.4, p=0.004).
Why the study?
Quality of life assesses physical and mental health, prompting prospective evaluation of quality of life in patients up to 10 years after coronary artery bypass graft surgery.
Does elective isolated CABG surgery improve long-term quality of life in adults?
Cohort (n=272)
No
Does elective isolated CABG surgery improve long-term quality of life in adults?
Absolute Event Rate: 59.5% vs 51.4%
p-value: p=0.004
Elective isolated CABG surgery provides durable improvements in both physical and mental components of quality of life up to 10 years post-procedure.
May support durable physical QoL gains after CABG; leaves open randomized confirmation of causality.
BACKGROUND: Quality of life (QoL) is a multifactorial concept that assesses physical and mental health. We prospectively studied the quality of life of patients undergoing coronary artery bypass graft (CABG) surgery using the Short-Form 36-item questionnaire (SF-36) up to 10 years after surgery. METHODS: Between January 2000 and December 2002, all patients undergoing elective isolated CABG in the cardiac & thoracic surgery department of a large university hospital in Eastern France underwent initial QoL evaluation with the SF-36. The same questionnaire was mailed to every patient annually (± 2 weeks around the date of surgery) up to 10 years after their operation. We recorded socio-demographic and clinical variables at inclusion. Predictors of impaired QoL at 10 years were identified by logistic regression. RESULTS: A total of 272 patients (213 men, 59 women) were enrolled; mean age at inclusion was 65 ± 10 years. At 10 years post-surgery, 81 patients had died (29.7%). The physical component summary (PCS) score was significantly higher at 5 years after surgery than at baseline (p < 0.01), and significantly lower at 10 years than at 5 years (p < 0.01), although there remained a significant difference between 10-year PCS and baseline score (p = 0.004). The mental component summary (MCS) score was significantly higher at 5 years than at the time of surgery (p < 0.001), and remained significantly higher compared to baseline at 10 years after surgery (p = 0.010). By multivariate analysis, diabetes and dypsnea were both associated with worse PCS at 10 years, while lower age was associated with better 10-year PCS. Only diabetes was associated with impaired MCS at 10 years. CONCLUSIONS: Cardiac surgery appears to durably and positively affect both physical and mental components of quality of life.
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Perrotti et al. (2019) conducted a cohort in Coronary artery disease (n=272). Coronary artery bypass graft (CABG) surgery vs. Baseline (pre-operative) was evaluated on SF-36 Physical Component Summary (PCS) score at 10 years (p=0.004). Coronary artery bypass graft surgery significantly improved the SF-36 Physical Component Summary score at 10 years compared to baseline (59.5 vs 51.4, p=0.004).