Why the study?
What is the incidence, location, and pathology of pulmonary homograft stenosis after the Ross operation?
Population
144 consecutive patients undergoing the Ross operation between 1993 and 2000
Design
Cohort
Follow-up
mean 48 months (up to 7 years)
Authors
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Supports serial surveillance after Ross; leaves open whether targeting early inflammation prevents progression.
What is the incidence, location, and pathology of pulmonary homograft stenosis after the Ross operation?
Pulmonary homograft stenosis after the Ross operation is clinically significant, affecting approximately 20% of patients by 7 years, and appears to be driven by an early postoperative inflammatory reaction causing extrinsic compression.
Carr-White et al. (2001) studied this question.
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