Key result
An exaggerated systolic blood pressure response to exercise testing increased the risk of sudden cardiac death by 73% (HR 1.73) in men without a history of cardiovascular disease.
Why the study?
It remains unclear whether an exaggerated SBP response to maximal exercise testing is directly or inversely related to SCD risk in men with and without a history of CVD.
Does an exaggerated systolic blood pressure response to maximal exercise testing predict sudden cardiac death in men with and without cardiovascular disease?
Population
Men with and without a history of CVD
Comparison
Exaggerated SBP response vs normal response during maximal exercise testing
Authors
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Exaggerated exercise SBP response was associated with higher SCD risk only in men without CVD; hypothesis-generating and should not yet change practice.
Cohort (n=2,410)
Does an exaggerated systolic blood pressure response to maximal exercise testing predict sudden cardiac death in men with and without cardiovascular disease?
Effect estimate: HR 1.73 (95% CI 1.07-2.82)
Absolute Event Rate: 7.7% vs 4.1%
An exaggerated systolic blood pressure response to maximal exercise testing is associated with an increased risk of sudden cardiac death in men without cardiovascular disease, but not in those with pre-existing cardiovascular disease.
Jae et al. (2019) conducted a cohort in Sudden cardiac death (n=2,410). Exaggerated systolic blood pressure (ESBP) response to exercise testing (≥210 mmHg) vs. Normal systolic blood pressure response to exercise testing (<210 mmHg) was evaluated on Sudden cardiac death (SCD) in men without a history of cardiovascular disease (HR 1.73, 95% CI 1.07-2.82). An exaggerated systolic blood pressure response to exercise testing increased the risk of sudden cardiac death by 73% (HR 1.73) in men without a history of cardiovascular disease.
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