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December 5, 2013Journal of Hypertension

Elevated systolic blood pressure during recovery from exercise and the risk of sudden cardiac death

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Key result

Elevated systolic blood pressure >195 mmHg during exercise recovery increased sudden cardiac death risk (HR 1.74), but the association became non-significant after adjusting for resting SBP.

Why the study?

Does elevated systolic blood pressure during recovery from exercise predict sudden cardiac death in middle-aged men?

Population

2,366 men (aged 42-61 years) from a representative general population sample

Comparison

Elevated systolic blood pressure at 2 min… vs Systolic blood pressure <170 mmHg at 2 min…

Design

Cohort

Follow-up

average 18.9 years

Authors

JLJari A. LaukkanenPreventive CardiologyPWPeter WilleitPreventive CardiologySKSudhir KurlPreventive Cardiology

Discussion

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Member takes

Overview

Recovery SBP elevation does not independently predict SCD beyond resting values; leaves open whether exercise testing adds prognostic information.

Study Design

Type

Cohort (n=2,366)

Structured PICO

Does elevated systolic blood pressure during recovery from exercise predict sudden cardiac death in middle-aged men?

P
Population
2,366 men aged 42-61 years followed for an average of 18.9 years to assess the association of systolic blood pressure during recovery from exercise with sudden cardiac death.
E
Exposure
Elevated systolic blood pressure (>195 mmHg) at 2 min recovery from progressive cycle ergometer exercise
C
Comparator
Systolic blood pressure <170 mmHg at 2 min recovery from exercise
O
Outcome
Sudden cardiac death (SCD) over an average follow-up of 18.9 yearshard clinical

Main Result

Hazard Ratio: 1.74 (95% CI 1.18–2.54)

p-value: p=0.005

Elevated systolic blood pressure during exercise recovery is associated with sudden cardiac death, but it does not provide independent prognostic value beyond resting blood pressure.

Cite This Study

Laukkanen et al. (2013) conducted a cohort in Sudden cardiac death (n=2,366). Elevated systolic blood pressure during recovery from exercise vs. SBP less than 170 mmHg was evaluated on Sudden cardiac death (SCD) (HR 1.74, 95% CI 1.18-2.54, p=0.005). Elevated systolic blood pressure >195 mmHg during exercise recovery increased sudden cardiac death risk (HR 1.74), but the association became non-significant after adjusting for resting SBP.

synapsesocial.com/papers/6a705f3235aa2c282ce1ae1ehttps://doi.org/10.1097/hjh.0000000000000066

Topics

Hypertension management
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prognostic significance of exercise versus resting blood pressure in hypertensive men.1991 · 104 citations
  2. 2Usefulness of the postexercise response of systolic blood pressure in the diagnosis of coronary artery disease.1984 · 69 citations
  3. 3Asymptomatic ST-segment depression during exercise testing and the risk of sudden cardiac death in middle-aged men: a population-based follow-up study2009 · 58 citations
  4. 4Exaggerated blood pressure response to exercise is associated with carotid atherosclerosis in apparently healthy men2006 · 88 citations
  5. 5Exercise Blood Pressure and Future Cardiovascular Death in Asymptomatic Individuals2010 · 167 citations